The Brazilian Journal of Infectious Diseases The Brazilian Journal of Infectious Diseases
Braz J Infect Dis 2017;21:325-32 - Vol. 21 Num.3 DOI: 10.1016/j.bjid.2017.01.009
Original article
Prevalence and risk factors for human papillomavirus infection among Chinese ethnic women in southern of Yunnan, China
Zulqarnain Balocha,1, Nafeesa Yasmeenb, Yuanyue Lic,1, Ke Mad, Xiaomei Wue, Shi-hua Yanga,, , Xueshan Xiac,,
a College of Veterinary Medicine, South China Agricultural University, Tianhe District, Guangzhou, China
b University of Veterinary and Animal Sciences, Department of Microbiology, Lahore, Pakistan
c Kunming University of Science and Technology, Faculty of Life Science and Technology, Kunming, China
d Medical College of Qingdao University, Department of Pharmacology, Qingdao, China
e The First People's Hospital of Yunnan Province, China
Received 06 December 2016, Accepted 23 January 2017
Abstract
Background

Dai is a major Chinese ethnic minority group residing in rural areas of the southern part of Yunnan. However, no data exist on the Human Papillomavirus (HPV) prevalence and genotype distribution among Dai women.

Method

A total of 793 participants (Dai=324, Han=251, other ethnic=218) were included in this study. PCR was performed to detect the HPV-positive samples, and genotyping was performed with an HPV Geno-Array.

Result

The overall HPV prevalence was very low among Dai women compared to the others. The prevalence of high-risk-HPV infections was significantly higher (p=0.001) among other ethnic women (22.0%) than that among Han (13.1%) and Dai women (7.1%). The overall HPV, high-risk-HPV, single and multiple infection prevalence among rural women were 12.9%, 12.1%, 12.3%, and 0.5%, respectively. HPV-16 (5.5%) was shown to be the most prevalent genotype, followed by HPV-52 (2.6%) and HPV-58 (2.4%). Urban women had relatively higher rates of overall HPV (16.0%), high-risk-HPV (14.1%), single genotype (11.9%), and multiple genotype (4.1%) infections. In urban women, HPV-52 (3.6%) was the most prevalent genotype, followed by HPV-39 (2.7%) and HPV-16 (1.2%). In the urban area, HPV prevalence was highest in women aged <29 years, but declined with increasing age. However, in rural women, the highest HPV prevalence was observed among women at older age (>50 years). Education and smoking habit were significantly associated with HPV infection among both rural and urban area women (p<0.001).

Conclusion

The prevalence and genotype distribution of HPV varied among ethnic women in urban and rural area of Yunnan Province.

Keywords
HPV, Prevalence, Dai, Genotypes, Rural, Urban, China
Braz J Infect Dis 2017;21:325-32 - Vol. 21 Num.3 DOI: 10.1016/j.bjid.2017.01.009